Speakers:  Emma Guttmann Yassky, Professor of Dermatology and Immunology in the Department of Dermatology as at the Icahn School of Medicine at Mount Sinai Medical Center & James G Krueger, Head of the Laboratory for Investigative Dermatology at The Rockefeller University.

Original Broadcast date:  August 22 2018

Dermatological diseases such as psoriasis, eczema, and alopecia are of great medical and socioeconomic significance, and are a leading cause of nonfatal disease burden for global health care. These diseases are often chronic and can have major physical and emotional impacts on sufferers, significantly reducing their quality of life. While such conditions may be classified as “skin diseases,” their underlying pathophysiology is complex, involving systemic inflammation and autoimmune processes. Exemplifying this complexity, diseases such as psoriasis are thought to be associated with increased cardiovascular risk, including myocardial infarction and stroke. Consequently, dermatological conditions represent both a challenge when it comes to penetrating their underlying biology and developing new and better therapies, and also an opportunity to gain insights into a wider range of mechanistically related diseases. Our panelists discuss how biomarkers can contribute to these goals by improving our biological understanding and helping us to develop more effective, targeted treatments for patients in the future.

The webinar covers the following points:

• The complex interplay of inflammatory and immunological processes in dermatological disease
• Recent progress in understanding pathophysiology and therapeutic opportunities
• Future developments and potential advances in this field.

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