Going beyond genomics with
Olink’s NGS-based proteomics


You know NGS.
Now you’re ready for Olink's NGS-based proteomics​.

Leveraging proteomics is simpler than ever with Olink’s NGS-based proteomics platform. This genomics guide to proteomics is designed for genomic researchers riding the multiomics wave—or ready to dive deeper. From foundational concepts to practical integration tips, this is your go-to guide for unlocking deeper biological insights—beyond the genome, with Olink.

Discover how Olink’s NGS-based proteomics—powered by our innovative products Olink® Explore HT and Olink® Reveal —makes it easier than ever to integrate high-throughput proteomics into your NGS pipeline and amplify the impact of your genomics research with multiomics insights.​ No prior proteomics expertise required.

Step into proteomics:
A glossary for genomics researchers

NGS is not only for genomics anymore: 

How it powers high-throughput protein analysis

From code to clarity:
Proteomics completes the picture

From idea to insight:
Start your NGS-based proteomics project with Olink

Get help starting now


Step into proteomics:
A glossary for genomics researchers

The future of biomedical discovery lies in connecting the dots across omics. As proteomics takes center stage alongside genomics, we’ve created this handy glossary to help you get up to speed—fast. Whether you’re exploring NGS-based proteomics for the first time or expanding into multiomics further, these essential terms will help you speak the language of proteins better and unlock new layers of insight in your research.

Get clarity on essential proteomics terms - flip through or download our glossary designed for genomics experts.

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Curious about what leading scientists say about going beyond genomics?

Watch our expert panel explore how proteomics is reshaping multiomics research.

NGS is not only for genomics anymore:
How it powers high-throughput protein analysis​

This is proteomics, the Olink way—right on your sequencer.​

​NGS-based proteomics from Olink combines next-generation sequencing with our proprietary Proximity Extension Assay (PEA™) to enable high-throughput protein identification and quantification—without the high instrument cost and specialized expertise required for mass spectrometry. This patented technology uses dual-antibody recognition and DNA barcoding to convert protein binding events into unique DNA sequences, readable by your existing NGS platform. The result? Unmatched specificity, sensitivity, and scalability—making proteomics finally accessible to genomics researchers, and seamlessly expanding your multiomics capabilities without the need of specialized proteomics expertise.​​ With Olink® Explore HT and Olink® Reveal, high-throughput proteomics integrates directly into your NGS workflow—now you can start unlocking the protein layer using the tools you already trust.

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Curious how PEA™ actually works?

Watch our short explanation on how Olink's Proximity Extension Assay works.

Want the technical deep dive?

Explore the white paper to understand the science behind PEA™ and how it enables Olink's NGS-based proteomics.

White paper

PEA™ - a high-multiplex immunoassay technology with qPCR or NGS readout

From code to clarity: Proteomics completes the picture

Just one simple step with Olink’s NGS-based proteomics —
a leap forward for your genomics research.

While genomics gives us the blueprint, proteomics reveals real-time biology in action. Integrating proteomics with genomics bridges the gap between genotype and phenotype, providing a more complete understanding of human health and disease. With Olink’s NGS-based proteomics, you can seamlessly add protein-level insights to your genomic data—enabling more accurate disease modeling, faster biomarker discovery, and accelerated development of targeted therapies and diagnostics.

What happens when genomics meets proteomics at scale?
Hear from visionaries behind the UK Biobank Pharma Proteomics Project and see how this approach redefines the future of precision medicine.

Curious how proteomic and polygenic risk scores work together?

Download our white paper to see how their integration is advancing early disease detection and prevention.

White paper

Integrating Polygenic Risk Scores and Proteomics: A New Paradigm for Predicting Health Risks

Looking for more inspiration or practical know-how from your peers?

Explore the Knowledge area on olink.com, your gateway to scientific publications, webinars, technical documents, and real-world stories from the research community using Olink’s NGS-based proteomics.

From Idea to Insight:
Start Your NGS-based proteomics project with Olink

You already read the genetic code and now see what it does in real-time with Olink NGS-based proteomics.

Ready to start? This section gives you the practical tools and guidance to kick off your multiomics journey. Discover more how Olink Explore HT and Olink Reveal make it easy to design, run, and interpret high-throughput protein studies—right from your existing NGS setup.

Not sure which solution best fits your research needs?

Explore the product comparison table below to understand how Olink® Reveal and Olink® Explore HT differ in library design, sample requirements and data outputs—so you can select the optimal platform for your multiomics strategy.

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Olink® Reveal

Proteins

>1,000

Sample

4 μl
Plasma, serum & more

Readout

NPX
Relative units

Runs on

NGS
Automated workflow

Dynamic range

fg-mg/mL
10 logs

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Olink® Explore HT

Proteins

5,400

Sample

2 μl
Plasma, serum & more

Readout

NPX
Relative units

Runs on

NGS
Automated workflow

Dynamic range

fg-mg/mL
10 logs

Take the first step into NGS-based proteomics with Olink® Reveal

Bring proteomics to your bench with Olink Reveal—a cost-effective, user-friendly library prep kit that lets you run high-throughput protein assays using your existing NGS setup. ​No specialized equipment. No prior proteomics expertise required.

Scale-up your NGS-based proteomics with Olink® Explore HT

Unlock proteogenomic projects with Olink Explore HT—quantify over 5,400 proteins with proven specificity and minimal sample volume. ​Built for scalability, seamlessly fitting into your current NGS workflow to power deeper biological insights.

Turn data into clear biological insights with Olink® Insight

Dive into Olink Insights, your free online bioinformatic support for drawing biological conclusions faster.

Start your NGS-based proteomics project with Olink

Whether you're planning your first study or scaling up, we'll help you choose the best solution and guide you through onboarding.

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