CSF biomarkers related to neuroinflammation using Olink assays in HIV and Alzheimer’s

 

Webinar title: "CSF biomarkers related to neuroinflammation using Olink assays in HIV and Alzheimer’s"

HIV and Alzheimer’s disease are associated with cognitive changes characterized by neuroinflammation or neurodegeneration, respectively. In this webinar, Dr. Galasko describes how Olink® PEA technology was used to profile proteins related to mild cognitive impairment in HIV and Alzheimer’s patients compared to controls using cerebrospinal fluid (CSF).

Dr. Galasko demonstrates that Olink® Target platforms allow the sensitive analysis of proteins in CSF, which has a lower total protein content than other sample types (e.g., plasma).

Watch the webinar to learn more about:

  • How Galasko and colleagues identified candidate biomarkers of cognitive impairment in HIV and Alzheimer’s disease.
  • The performance of Olink® Target 96 Inflammation, Neuro-exploratory, and Neurology panels in CSF, where 42 – 77% proteins were detected in > 75% CSF samples.
  • Results from comparisons between Olink® Target 48 and Olink® Target 96 Inflammation panels, which revealed a strong correlation between proteins targeted by both types of panels.

Speaker

Douglas-Galasko,-MD-1

Dr. Gouglas Galasko

Professor of Neurosciences

University of California San Diego

Watch the recording now!