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Olink Signature Q100 makes protein biomarker analysis easier than ever

Oct 11, 2021 9:30:00 AM / by Olink posted in Insider, Basic research, Olink technology

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At Olink we strive to always improve our platform and products to make it easier for you, the customer, to conduct your protein biomarker analysis. To this end we have collaborated with Fluidigm to make protein analysis simpler than ever when running our 48- and 96-plex Olink® Target panels, and our Olink® Focus custom-designed panels (up to 24-plex).

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Can inflammation biomarkers classify different forms of diabetes?

Aug 30, 2021 9:30:00 AM / by Olink posted in Metabolic diseases, Clinical research, Publications

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Diabetes is a complex disease characterized by a combination of different and little understood, causes. The current classification system for the disease characterizes diabetes into three broad types: type 1 diabetes, type 2 diabetes, and gestational diabetes, but these three categories do not adequately reflect its sheer heterogeneity. This has severe negative implications for the planning of treatment regimens and identifying which patients are at risk of developing complications or comorbidities. Building on previous research which identified five novel diabetes subgroups in Scandinavian diabetes patient cohorts, this study sought to comprehensively characterize differences in inflammation biomarkers between these subgroups using Olink’s inflammation biomarker panel.

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Introducing CORAL, a neurology research consortium using Olink data

Aug 24, 2021 3:36:56 PM / by Olink posted in Neurology, Proteomics, Publications

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In its mission to accelerate proteomics together, Olink encourages the advancement of science through comprehensive support of its customers in their own studies to achieve better insight into their areas of research. Sometimes, this may be achieved through collaboration with other scientists in their fields. As a result, Olink has played a part in creating several consortia involving Olink customers with similar areas of interest, such as SCALLOP, where like-minded researchers work together to publish high-impact papers investigating the association of genes and proteins included in Olink protein panels.

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Protein biomarkers may predict severe traumatic brain injury mortality

Aug 16, 2021 9:30:00 AM / by Olink posted in Neurology, Biomarkers, Proteomics

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How proteogenomics can improve drug discovery and development

Aug 9, 2021 9:30:00 AM / by Olink posted in Insider, Precision medicine, Drug discovery & development, Proteogenomics

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With the advancement of available technologies in recent years, researchers are fast becoming aware of the advantages of using proteomics in their research to better understand human biology and disease and to drive pharmaceutical development towards new and improved therapies. Anders Mälarstig, the director of human genetics at Pfizer, came to this realization early on. While he began his research career using genetics to understand cardiovascular disease, he soon turned to proteomics, and specifically protein quantitative trait loci (pQTLs) to take his research one step further. In the following interview, Dr. Mälarstig makes the case for this proteogenomics approach to advance basic and clinical research and speaks to its advantages in the drug discovery and development space.

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How proteomics using Olink helped advance diabetic kidney disease research

Aug 2, 2021 9:30:00 AM / by Olink posted in Metabolic diseases, Nephrology, Biomarkers, Clinical research, Proteomics

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Dr. Andrzej Krolewski (Find his profile here), the head of the Genetics and Epidemiology section of the Harvard Medical School, has been working on the genetics of type 1 and type 2 diabetes. For the last 30 years, he has been actively investigating diabetic kidney disease in patient cohorts from the Joslin diabetes center, where he is also a researcher.

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Developing a high-performance biomarker panel for Alzheimer’s disease

Jul 21, 2021 6:31:32 PM / by Olink posted in Neurology, Biomarkers, Clinical research, Publications

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Utilizing proteogenomics technology for novel drug target discovery

Jul 13, 2021 3:24:44 PM / by Olink posted in Precision medicine, Drug discovery & development

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High-throughput multiplexed proteomic technology is leading the way to the latest developments in pre-clinical disease analysis in drug discovery. The pharmaceutical industry is now increasing its efforts in the discovery of novel drug targets by using protein quantitative trait loci (pQTLs), which allows for a more confident inference of disease causality and associated protein regulation. This has the potential to revolutionize the drug discovery process and a major academia-industry consortium is at the forefront of efforts to do just that.

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Dr. Chris Whelan speaks on the topic “Proteomics at Population Scale”

Jul 5, 2021 9:30:00 AM / by Olink posted in Biomarkers, Proteomics

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Proteins diagnostic of lung cancer up to 5 years before disease onset

Jun 28, 2021 9:30:00 AM / by Olink posted in Immunotherapy, Oncology

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